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ELIXIR.NO - a Research Infrastructure Project

The ELIXIR.NO project is coordinated by the University of Bergen and includes the Universities in Oslo, Trondheim, Tromso and Aas. It receives funding from the Research Council of Norway through its research infrastructure program and is also supported by the participating institutions. Read more...

Recent Publications

(2015) "A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine"
Hansen, M.F.; Johansen, J.; Bjornevoll, I.; Sylvander, A.E.; Steinsbekk, K.S.; Saetrom, P.; Sandvik, A.K.; Drablos, F.; Sjursen, W. Familial cancer (): view article

(2015) Omland T, de Lemos JA, Holmen OL, Dalen H, Benth JÅ , NygÃ¥rd S, Hveem K, Røsjø H. Impact of Sex on the Prognostic Value of High-Sensitivity Cardiac Troponin I in the General Population: The HUNT Study. Clin Chem. 2015 Feb 18. pii: clinchem.2014.234369. [Epub ahead of print] PubMed PMID: 25695851.

(2015) Ottesen AH, Louch WE, Carlson CR, Landsverk OJ, Kurola J, Johansen RF, Moe MK, Aronsen JM, Høiseth AD, Jarstadmarken H, NygÃ¥rd S, BjørÃ¥s M, Sjaastad I, Pettilä V, Stridsberg M, Omland T, Christensen G, Røsjø H. Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling. J Am Coll Cardiol. 2015 Feb 3;65(4):339-51. doi: 10.1016/j.jacc.2014.10.065. PubMed PMID: 25634832.

(2015) Ricanek P, Lunde LK, Frye SA, Støen M, NygÃ¥rd S, Morth JP, Rydning A, Vatn MH, Amiry-Moghaddam M, Tønjum T. Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease. Clin Exp Gastroenterol. 2015 Jan 9;8:49-67. doi: 10.2147/CEG.S70119. eCollection 2015. PubMed PMID: 25624769; PubMed Central PMCID: PMC4296881.

(2015) Bergseng E, Dørum S, Arntzen MØ, Nielsen M, NygÃ¥rd S, Buus S, de Souza GA, Sollid LM. Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires. Immunogenetics. 2015 Feb;67(2):73-84. doi: 10.1007/s00251-014-0819-9. Epub 2014 Dec 12. PubMed PMID: 25502872; PubMed Central PMCID: PMC4297300.

(2014) Berg A., Hoivik E.A., Mjøs S., Holst F., Werner H.M., Tangen I.L., Taylor-Weiner A., Gibson W.J., Kusonmano K., Wik E., Trovik J., Halle M.K., Oyan A.M., Kalland K.H., Cherniack A.D., Beroukhim R., Stefansson I., Mills G.B., Krakstad C. and Salvesen H.B. Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients. Oncotarget. 2014. 

(2014) Tangen I.L., Werner H.M., Berg A., Halle M.K., Kusonmano K., Trovik J., Hoivik E.A., Mills G.B., Krakstad C. and Salvesen H.B. Loss of progesterone receptor links to high proliferation and increases from primary to metastatic endometrial cancer lesions. European Journal of Cancer. 2014;50(17):3003-10. 

(2014) Engerud H., Tangen I.L., Berg A., Kusonmano K., Halle M.K., Oyan A.M., Kalland K. H., Stefansson I., Salvesen H.B. and Krakstad C. High level of HSF1 associates with aggressive endometrial carcinoma and suggests potential for HSP90 inhibitors. British Journal of Cancer. 2014;111(1):78-84. 

(2014) Wik E, Trovik J, Kusonmano K, Birkeland E, Raeder MB, Pashtan I, Hoivik EA, Krakstad C, Werner HM, Holst F, Mjøs S, Halle MK, Mannelqvist M, Mauland KK, Oyan AM, Stefansson IM, Petersen K, Simon R, Cherniack AD, Meyerson M, Kalland KH, Akslen LA, Salvesen HB. Endometrial Carcinoma Recurrence Score (ECARS) validates to identify aggressive disease and associates with markers of epithelial-mesenchymal transition and PI3K alterations. Gynecol Oncol. 2014 Sep;134(3):599-606. doi: 10.1016/j.ygyno.2014.06.026. Epub 2014 Jul 1. PMID:    24995579

(2014) Tangen IL, Krakstad C, Halle MK, Werner HM, Oyan AM, Kusonmano K, Petersen K, Kalland KH, Akslen LA, Trovik J, Hurtado A, Salvesen HB. Switch in FOXA1 status associates with endometrial cancer progression. PLoS One. 2014 May 21;9(5):e98069. doi: 10.1371/journal.pone.0098069. eCollection 2014. PMID: 24849812

(2014) Hoivik EA, Kusonmano K, Halle MK, Berg A, Wik E, Werner HM, Petersen K, Oyan AM, Kalland KH, Krakstad C, Trovik J, Widschwendter M, Salvesen HB. Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene. Oncotarget. 2014 Feb 28;5(4):1052-61. PMID: 24658009

(2014) NygÃ¥rd S, Reitan T, Clancy T, Nygaard V, Bjørnstad J, Skrbic B, Tønnessen T, Christensen G, Hovig E. Identifying pathogenic processes by integrating microarray data with prior knowledge. BMC Bioinformatics. 2014 Apr 24;15:115. doi: 10.1186/1471-2105-15-115. PubMed PMID: 24758699; PubMed Central PMCID: PMC4006456.

(2014) Wollen EJ, Kwinta P, Bik-Multanowski M, Madetko-Talowska A, Sejersted Y, Wright MS, Günther CC, NygÃ¥rd S, Saugstad OD, Pietrzyk JJ. Hypoxia-reoxygenation affects whole-genome expression in the newborn eye. Invest Ophthalmol Vis Sci.2014 Mar 10;55(3):1393-401. doi: 10.1167/iovs.13-13159. PubMed PMID: 24458145.

(2014) Wu X, Sagave J, Rutkovskiy A, Haugen F, Baysa A, NygÃ¥rd S, Czibik G, Dahl CP, Gullestad L, Vaage J, Valen G. Expression of bone morphogenetic protein 4 and its receptors in the remodeling heart. Life Sci. 2014 Mar 3;97(2):145-54. doi: 10.1016/j.lfs.2013.12.030. Epub 2014 Jan 4. PubMed PMID: 24398041.

(2014) Wollen EJ, Sejersted Y, Wright MS, Madetko-Talowska A, Bik-Multanowski M, Kwinta P, Günther CC, NygÃ¥rd S, Løberg EM, Ystgaard MB, Pietrzyk JJ, Saugstad OD. Transcriptome profiling of the newborn mouse brain after hypoxia-reoxygenation: hyperoxic reoxygenation induces inflammatory and energy failure responsive genes. Pediatr Res. 2014 Apr;75(4):517-26. doi: 10.1038/pr.2013.249. Epub 2013 Dec 27. PubMed PMID: 24375083. 

 

 

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About ELIXIR.NO and ELIXIR

ELIXIR.NO is a project supported by the Research Council of Norway aimed to build a Norwegian Bioinformatics research infrastructure and to establish a Norwegian ELIXIR Node.

ELIXIR is a pan-European research infrastructure - read more at www.elixir-europe.org